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The Gould–Jacobs reaction is an organic synthesis for the preparation of quinolines (more specifically, a 4-Quinolinol). In this reaction aniline or an aniline derivative first reacts with malonic acid derivative ethyl ethoxymethylenemalonate with substitution of the ethoxy group by nitrogen. A benzannulation takes place by application of heat to a quinoline. The ester group is hydrolysed by sodium hydroxide to the carboxylic acid and decarboxylation again by application of heat to 4-hydroxyquinoline.
Further reading:
Examples
An example is the synthesis of 4,7-dichloroquinoline
References
Gould–Jacobs reaction Wikipedia(Text) CC BY-SA