Glyphidocera lactiflosella, the five-spotted glyphidocera moth, is a moth in the Autostichidae family. It was described by Chambers in 1878. It is found in North America, where it has been recorded from Alabama, Arkansas, Florida, Georgia, Louisiana, Maine, Mississippi, North Carolina, South Carolina, Tennessee and Texas.
The wingspan is about 12.7 mm. The forewings are pale cream-color, sparsely dusted with brown, with a small brown spot touching the fold above, near the base of the wing, another a little farther back, and yet farther back near the middle two spots, one on the fold, the other on the disc. Sometimes these two last spots are confluent. There is a transverse brown streak at the end of the cell, and a distinct brown line curving around the base of the apical cilia. The hindwings are white, tinged with silvery. Adults are on wing from January to October.