Glycosylceramidase

In enzymology, a glycosylceramidase (EC 3.2.1.62) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are glycosyl-N-acylsphingosine and H₂O, whereas its two products are N-acylsphingosine and sugar.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is glycosyl-N-acylsphingosine glycohydrolase. Other names in common use include phlorizin hydrolase, phloretin-glucosidase, glycosyl ceramide glycosylhydrolase, cerebrosidase, phloridzin beta-glucosidase, lactase-phlorizin hydrolase, and phloridzin glucosidase.