Neha Patil (Editor)

Glycine dehydrogenase

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
  
1.4.1.10

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37255-40-6

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a glycine dehydrogenase (EC 1.4.1.10) is an enzyme that catalyzes the chemical reaction

glycine + H2O + NAD+ glyoxylate + NH3 + NADH + H+

The 3 substrates of this enzyme are glycine, H2O, and NAD+, whereas its 4 products are glyoxylate, NH3, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycine:NAD+ oxidoreductase (deaminating).

This should not be confused with:

the glycine dehydrogenase (decarboxylating), which is another name for the Glycine cleavage system P-protein (EC 1.4.4.2).

or the glycine dehydroganse (cyanide forming)(EC 1.4.99.5).

or the glycine dehydrogenase (cytochrome) (EC 1.4.2.1).

References

Glycine dehydrogenase Wikipedia