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Glycerophosphocholine cholinephosphodiesterase

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EC number
  
3.1.4.38

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
60063-78-7

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a glycerophosphocholine cholinephosphodiesterase (EC 3.1.4.38) is an enzyme that catalyzes the chemical reaction

sn-glycero-3-phosphocholine + H2O glycerol + choline phosphate

Thus, the two substrates of this enzyme are sn-glycero-3-phosphocholine and H2O, whereas its two products are glycerol and choline phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is sn-glycero-3-phosphocholine cholinephosphohydrolase. This enzyme is also called L-3-glycerylphosphinicocholine cholinephosphohydrolase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1WRA.

References

Glycerophosphocholine cholinephosphodiesterase Wikipedia