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Glyceraldehyde 3 phosphate dehydrogenase (NADP ) (phosphorylating)

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EC number
  
1.2.1.13

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37250-87-6

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) (EC 1.2.1.13) is an enzyme that catalyzes the chemical reaction

Contents

D-glyceraldehyde 3-phosphate + phosphate + NADP+ ⇌ 3-phospho-D-glyceroyl phosphate + NADPH + H+

The 3 substrates of this enzyme are D-glyceraldehyde 3-phosphate, phosphate, and NADP+, whereas its 3 products are 3-phospho-D-glyceroyl phosphate, NADPH, and H+.

Function

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. This enzyme participates in the Calvin cycle which is an autotrophic carbon fixation pathway.

Nomenclature

The systematic name of this enzyme class is D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating). Other names in common use include:

  • dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating)
  • GAPDH
  • glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating)
  • glyceraldehyde-3-phosphate dehydrogenase (NADP) (phosphorylating)
  • NADP-dependent glyceraldehyde phosphate dehydrogenase
  • NADP-glyceraldehyde phosphate dehydrogenase
  • NADP-glyceraldehyde-3-phosphate dehydrogenase
  • NADP-triose phosphate dehydrogenase
  • triosephosphate dehydrogenase (NADP)

    • References

    Glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) Wikipedia
    (Text) CC BY-SA