EC number 6.2.1.6 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9023-68-1 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a glutarate-CoA ligase (EC 6.2.1.6) is an enzyme that catalyzes the chemical reaction
ATP + glutarate + CoAThe 3 substrates of this enzyme are ATP, glutarate, and CoA, whereas its 3 products are ADP, phosphate, and glutaryl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is glutarate:CoA ligase (ADP-forming). Other names in common use include glutaryl-CoA synthetase, and glutaryl coenzyme A synthetase. This enzyme participates in fatty acid metabolism and lysine degradation.
References
Glutarate—CoA ligase Wikipedia(Text) CC BY-SA