Schofield trained in both fine arts and business, earning a BFA from Pratt Institute and an MBA from Golden Gate University. His career began as an artist and art director with the New Jersey video game company Absolute Entertainment. He then relocated to Seattle to join the West Coast's burgeoning video games industry. His professional influences included Asteroids, Moon Patrol, Gunstar Heroes, Disruptor and the Contra series, followed later by Resident Evil, Gears of War, and the franchise he would eventually contribute to, Modern Warfare.
As a vice president at Crystal Dynamics, Schofield headed development on two of the studio's franchises: Gex and Legacy of Kain. Moving to EA Redwood Studios as general manager of the company's Visceral Games, he collaborated with Bret Robbins, including the popular Lord of the Rings video series and 007: From Russia with Love.
Schofield's reputation grew with the 2008 title Dead Space, which the magazine Edge called "a work of passionate sci-fi horror that became the one of most commercially successful new properties of the year." Schofield has said that the film Event Horizon inspired him to create a game that fused the genres of Science fiction and Horror. The game's theme of humans in space losing perspective to their place in the universe is influenced by the works of Arthur C. Clarke, after whom the game character Isaac Clarke was named.
Schofield, executive producer on the project, worked with Michael Condrey, senior development director. The game launched a franchise of sequels, comics, novels and films, and went on to win more than 80 industry awards, including the Academy of Interactive Arts & Sciences' Action Game of the Year and two awards from the British Academy of Film and Television Arts. During his time at EA Redwood Studios, the studio was ranked 17th in the top 50 Game Developers List of 2009 by Game Developer Research. Edge named him one of the Hot 100 Game Developers of 2009.
In 2009, Schofield and Condrey created Sledgehammer Games, with Schofield as general manager and Condrey as chief operating officer. They retained those roles when, that November, Activision acquired the company as a wholly owned development studio operating on an independent model.
Schofield was also a storyboard director and created over 100 characters for the animated series The Adventures of the Galaxy Rangers.
Schofield grew up in New Jersey and, with the encouragement of his parents, began drawing and taking art lessons at an early age. He is married with three children, paints in his spare time, and is a habitual exerciser, both cardiovascular and weight training, averaging once a day while on deadline, twice that when not.