Gillette is a surname. Notable people with the surname include:
Gillette (singer) (born 1974), full name Sandra Gillette, American R&B-dance artistAnita Gillette (born 1936), American actress and game-show panelistArthur Gillette (1863–1921), American pediatric orthopedic surgeonChester Gillette (1883–1908), American murdererClarence Preston Gillette (1859–1941), American entomologistDouglas W. Gillette (1918-1942), American naval officerElizabeth V. Gillette (1874–1965), New York physician, assemblywoman 1920Guy Gillette (1879–1973), American politician from IowaGuy Gillette (photographer) (1922-2013), American photographerJim Gillette (born 1967), American singerKing Camp Gillette (1855–1932), American businessman and founder of the Gillette Safety Razor CompanyWilliam Gillette (1853–1937), American actor famous for his stage version of Sherlock Holmes