Trisha Shetty (Editor)

Gemeprost

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Routes of administration
  
Pessary

CAS Number
  
64318-79-2

Molar mass
  
394.545 g/mol

ATC code
  
G02AD03 (WHO)

PubChem CID
  
5282237

Gemeprost

AHFS/Drugs.com
  
International Drug Names

Synonyms
  
methyl (E)-7-[(1R,2S,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyl-oct-1-enyl]-5-oxo-cyclopentyl]hept-2-enoate

Gemeprost (16, 16-dimethyl-trans-delta2 PGE1 methyl ester) is an analogue of prostaglandin E1.

Contents

Clinical use

It is used as a treatment for obstetric bleeding.

It is used with mifepristone to terminate pregnancy up to 24 weeks gestation.

Side effects

Vaginal bleeding, cramps, nausea, vomiting, loose stools or diarrhea, headache, muscle weakness; dizziness; flushing; chills; backache; dyspnoea; chest pain; palpitations and mild pyrexia. Rare: Uterine rupture, severe hypotension, coronary spasms with subsequent myocardial infarctions.

References

Gemeprost Wikipedia