EC number 2.3.1.18 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9029-94-1 BRENDA BRENDA entry KEGG KEGG entry | |
Galactoside O-acetyltransferase (also known as thiogalactoside transacetylase) is an enzyme encoded by the lacA gene in E. coli. The protein plays a role in cell detoxification.
Contents
Reaction
It catalyzes the following reaction:
acetyl-CoA + beta-D-galactoside → CoA + 6-acetyl-beta-D-galactoside
Structure
In E. coli, thiogalactoside transacetylase is a dimer. Its monomer consists of 202 amino acid residues. The protein has a molecular weight of 22,671.
The amino terminus of the protein is heterogenous because the initiator methionine is only partially cleaved. The protein is found in the cell cytoplasm and contains a highly hydrophobic segment in its center.
References
Galactoside O-acetyltransferase Wikipedia(Text) CC BY-SA