Entrez 2983 | Ensembl ENSG00000061918 | |
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Aliases GUCY1B3, GC-S-beta-1, GC-SB3, GUC1B3, GUCB3, GUCSB3, GUCY1B1, guanylate cyclase 1, soluble, beta 3, guanylate cyclase 1 soluble subunit beta External IDs MGI: 1860604 HomoloGene: 664 GeneCards: GUCY1B3 | ||
Guanylate cyclase soluble subunit beta-1 is an enzyme that in humans is encoded by the GUCY1B3 gene.
Contents
Function
Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.
Interactions
GUCY1B3 has been shown to interact with Heat shock protein 90kDa alpha (cytosolic), member A1 and Endothelial NOS.
References
GUCY1B3 Wikipedia(Text) CC BY-SA