Entrez 2894 | Ensembl ENSG00000182771 | |
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Aliases GRID1, GluD1, glutamate ionotropic receptor delta type subunit 1 External IDs MGI: 95812 HomoloGene: 69017 GeneCards: GRID1 | ||
Glutamate receptor delta-1 subunit also known as GluD1 or GluRĪ“1 is a protein that in humans is encoded by the GRID1 gene.
Contents
Function
This gene encodes a subunit of glutamate receptor ligand-gated ion channel. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.
Clinical significance
Several genetic epidemiology studies have shown a strong association between several variants of the GRID1 gene and increased risk of developing schizophrenia.
References
GRID1 Wikipedia(Text) CC BY-SA