Entrez 222545 | Ensembl ENSG00000173612 | |
External IDs MGI: 2429498 HomoloGene: 17529 GeneCards: GPRC6A |
G protein-coupled receptor family C group 6 member A is a protein that in humans is encoded by the GPRC6A gene. This protein functions as a receptor of -α-amino acids, cations (e.g., calcium), osteocalcin, and steroids. It is a membrane androgen receptor.
Clinical significance
GPRC6A has also been linked to prostate cancer progression, and it has been shown to mediate rapid, non-genomic prostate cancer cell responses to testosterone.
References
GPRC6A Wikipedia(Text) CC BY-SA