Species Human Entrez 26354 | Human Mouse Ensembl ENSG00000163938 | |
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Aliases GNL3, C77032, E2IG3, NNP47, NS, G protein nucleolar 3 External IDs MGI: 1353651 HomoloGene: 56670 GeneCards: GNL3 | ||
Guanine nucleotide-binding protein-like 3, also known as nucleostemin, is a protein that in humans is encoded by the GNL3 gene. It is found within the nucleolus that binds p53. Nucleostemin regulates the cell cycle and affects cell differentiation, decreasing in amount as this differentiation progresses. It is a marker for many stem cells and cancer cells.
Interactions
GNL3 has been shown to interact with Mdm2 and P53.
References
GNL3 Wikipedia(Text) CC BY-SA