Entrez 79623 | Ensembl ENSG00000158089 | |
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Aliases GALNT14, GALNT15, GalNac-T10, GalNac-T14, polypeptide N-acetylgalactosaminyltransferase 14 External IDs MGI: 1918935 HomoloGene: 56997 GeneCards: GALNT14 | ||
Polypeptide N-acetylgalactosaminyltransferase 14 is an enzyme that in humans is encoded by the GALNT14 gene.
GALNT14 (EC 2.4.1.41) belongs to a large subfamily of glycosyltransferases residing in the Golgi apparatus. GALNT enzymes catalyze the first step in the O-glycosylation of mammalian proteins by transferring N-acetyl-D-galactosamine (GalNAc) to peptide substrates.[supplied by OMIM]
SNPs on GALNT14 have been shown to be associated to the chemotherapy responses of patients with advanced hepatocellular carcinoma.
References
GALNT14 Wikipedia(Text) CC BY-SA