EC number 3.1.3.46 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 81611-75-8 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) is an enzyme that catalyzes the chemical reaction
beta-D-fructose 2,6-bisphosphate + H2OThus, the two substrates of this enzyme are beta-D-fructose 2,6-bisphosphate and H2O, whereas its two products are D-fructose 6-phosphate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase. Other names in common use include fructose-2,6-bisphosphatase, and D-fructose-2,6-bisphosphate 2-phosphohydrolase. This enzyme participates in fructose and mannose metabolism.
Structural studies
As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes 1BIF, 1C7Z, 1C80, 1C81, 1FBT, 1K6M, 1TIP, 2AXN, 2BIF, 2DWO, 2DWP, 2I1V, and 3BIF.