Frances of Rome (1384-1440), Italian saint, mystic, organizer of charitable services and Benedictine oblate who founded a religious community of oblates
Frances Carr, Countess of Somerset (1590-1632), central figure in a famous scandal and murder
Frances Davidson, Viscountess Davidson (1894-1985), British politician and Member of Parliament
Frances Grey, Duchess of Suffolk (1517–1559), granddaughter of Henry VII of England and mother of Queen Jane Grey
Frances Hyde, Countess of Clarendon (baptised 1617, died 1667), mother-in-law of King James II of England and maternal grandmother of Mary II and Queen Anne
Frances Newton, Lady Cobham (1539-1592), one of the closest friends of Queen Elizabeth I of England
Frances Radclyffe, Countess of Sussex (1531-1589)
Frances Seymour, Duchess of Somerset (1599-1674)
Frances Stewart, Duchess of Richmond, as known as 'La Belle Stuart', the face of Britannia
Frances Talbot, Countess of Tyrconnel (c. 1647-1730)
Frances Vane, Viscountess Vane (1715-1788), British memoirist known for her highly public adulterous relationships
Frances Waldegrave, Countess Waldegrave (1821–1879), a leader and hostess of society
Frances Walsingham, Countess of Essex and Countess of Clanricarde (1567–1633), daughter of Elizabeth I's Secretary of State, wife of Sir Philip Sidney; Robert Devereux, 2nd Earl of Essex; and Richard Burke, 4th Earl of Clanricarde
Frances Black (born 1960), Irish singer
Frances Bean Cobain (born 1992), daughter of Nirvana frontman Kurt Cobain and singer Courtney Love
Frances Conroy, American actress
Frances Cornford (1886-1960), English poet
Frances Dodge (1914-1971), American internationally known horsewoman
Frances Scott Fitzgerald (1921–1986), American journalist
Frances Burney (1752–1840), English novelist, diarist and playwright
Frances Hodgson Burnett (1849–1924), English playwright and author
Frances Farmer, American actress
Frances Fisher, American actress
Frances FitzGerald (journalist) (born 1940), U.S. journalist and author
Frances Fitzgerald (politician) (born 1950), Irish Fine Gael politician
Frances Benjamin Johnston (1864–1952), American photographer and photojournalist
Frances Kirwan (1959-), British mathematician
Frances Latham (1610-1677), colonial woman in Rhode Island known as "the Mother of Governors" for having 10 governors among her direct descendents
Frances Lupton (1821-1892), English reformer for female education
Frances MacDonald (1873–1921), Scottish artist
Frances McDormand, American actress
Frances Nelson (1761-1831), wife of Admiral Horatio Nelson
Frances Osborne (born 1969), British author
Frances Folsom Cleveland Preston (1864-1937), wife of US President Grover Cleveland
Frances Schreuder (1938-2004), American murderer in the Franklin Bradshaw murder.
Frances Alice Shepherd, Canadian academic
Frances T. Sullivan, New York State assemblywoman 1991–2002