François-Xavier is a French masculine given name. Notable people with the name include:
François-Xavier Archambault (1841-1893), a lawyer and political figure in QuebecFrançois-Xavier Audouin (1765-1837), a French clergyman and politician during the French RevolutionFrançois-Xavier Babineau (1825-1890), a Canadian Catholic priestFrançois-Xavier Bélanger (1833-1882), a French-Canadian naturalist and museum curatorFrançois-Xavier Bellamy (born 1985), French philosopher and politicianFrançois-Xavier Brunet (1868-1922), a Canadian Roman Catholic priest and bishop of Mont-Laurier, QuébecFrançois-Xavier Cloutier (1848-1934), a Canadian Roman Catholic BishopFrançois-Xavier de Donnea (born 1941), a Belgian politicianFrançois-Xavier de Feller (1735-1802), a Belgian authorFrançois-Xavier de Peretti, a French politicianFrançois-Xavier Dulac (1841-1890), a farmer, merchant and political figure in QuebecFrançois-Xavier Dumortier (born 1948), a French Roman Catholic priestFrançois-Xavier Fabre (1766–1837), a French painter of historical subjectsFrançois-Xavier Garneau (1809-1866), a French Canadian notary, poet, civil servant and liberalFrançois-Xavier Lalanne (1927-2008), a French sculptor and engraverFrançois-Xavier Larue (1763-1855), a farmer, notary and political figure in Lower CanadaFrançois-Xavier Lemieux (1811-1864), a French Canadian lawyer and politicianFrançois-Xavier Lemieux (Quebec MLA) (1851-1933), a Quebec lawyer, judge and political figureFrançois-Xavier Malhiot (1781-1854), a merchant, seigneur and political figure in Lower CanadaFrançois-Xavier Méthot (1796-1853), a Quebec businessman and political figureFrançois-Xavier Nzuwonemeye, a former Rwandan soldier chiefly known for his alleged role in the Rwandan GenocideFrançois-Xavier Octavie Fontaine (1762-1812), a French military in the American War of Independence, the French Revolutionary Wars and the Napoleonic WarsFrançois-Xavier Ortoli (1925-2007), a French Gaullist politician and businessmanFrançois-Xavier Paradis (1844-1910), a Canadian politicianFrançois-Xavier Paré (1793-1836), a political figure in Lower CanadaFrançois-Xavier Poizat (born 1989), a French pianistFrançois-Xavier Roth (born 1971), a French conductorFrançois-Xavier Tessier (1799-1835), a doctor, publisher and political figure in Lower CanadaFrançois-Xavier Verschave (1945-2005), the founders of the French NGO SurvieFrançois-Xavier Villain (born 1950), a member of the National Assembly of FranceFrançois-Xavier Wurth-Paquet (1801-1885), a Luxembourgian politician, jurist and archaeologist