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Formyltetrahydrofolate deformylase

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EC number  3.5.1.10
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  9025-08-5
BRENDA  BRENDA entry
KEGG  KEGG entry

In enzymology, a formyltetrahydrofolate deformylase (EC 3.5.1.10) is an enzyme that catalyzes the chemical reaction

10-formyltetrahydrofolate + H2O formate + tetrahydrofolate

Thus, the two substrates of this enzyme are 10-formyltetrahydrofolate and H2O, whereas its two products are formate and tetrahydrofolate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 10-formyltetrahydrofolate amidohydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism and one carbon pool by folate.

References

Formyltetrahydrofolate deformylase Wikipedia


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