EC number 3.5.1.49 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9013-59-6 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a formamidase (EC 3.5.1.49) is an enzyme that catalyzes the chemical reaction
formamide + H2OThus, the two substrates of this enzyme are formamide and H2O, whereas its two products are formate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is formamide amidohydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism and nitrogen metabolism.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 2DYU, 2DYV, 2E2K, and 2E2L.
References
Formamidase Wikipedia(Text) CC BY-SA