Supriya Ghosh (Editor)

Flesinoxan

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Routes of administration
  
Oral

CAS Number
  
98206-10-1

IUPHAR/BPS
  
1

ATC code
  
none

PubChem CID
  
57347

Molar mass
  
415.458 g/mol

Flesinoxan

Legal status
  
In general: uncontrolled

What does flesinoxan mean


Flesinoxan (DU-29,373) is a potent and selective 5-HT1A receptor partial/near-full agonist of the phenylpiperazine class. Originally developed as a potential antihypertensive drug, flesinoxan was later found to possess antidepressant and anxiolytic effects in animal tests. As a result, it was investigated in several small human pilot studies for the treatment of major depressive disorder, and was found to have robust effectiveness and very good tolerability. Unfortunately however, due to "management decisions", the development of flesinoxan was stopped and it was not pursued any further.

Contents

In patients, flesinoxan enhances REM sleep latency, decreases body temperature, and increases ACTH, cortisol, prolactin, and growth hormone secretion.

How to pronounce flesinoxan


References

Flesinoxan Wikipedia