Neha Patil

Filaminast

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ATC code  None
CAS Number  141184-34-1
DrugBank  DB02660
Molar mass  292.33 g/mol
Legal status  Development terminated
PubChem CID  9578243
ChemSpider  7852607
Filaminast httpsuploadwikimediaorgwikipediacommonsthu

How to pronounce filaminast


Filaminast (code name WAY-PDA 641) was a drug candidate developed by Wyeth-Ayerst. It is a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and an analog of rolipram, which served as a prototype molecule for several development efforts. It was discontinued after a Phase II trial showed that its therapeutic window was too narrow; it could not be dosed high enough without causing significant side effects (nausea and vomiting), which was a problem with the rolipram class of molecules.

References

Filaminast Wikipedia


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