12817 Federica (1996 FM16), a Main-belt Asteroid discovered in 1996
Federica Constantini (born 1988), Italian figure skater
Federica Faiella (born 1981), Italian ice dancer
Federica Falzon (born 2003), Maltese child opera singer
Federica Fontana (born 1977), Italian television sports announcer
Federica Guzmán, (born 1981), the former Miss Venezuela World 2006
Federica Haumuller (born 1972), Argentinian former professional tennis player
Federica Montseny (1905–1994), Spanish anarchist, intellectual and Minister of Health
Federica Pellegrini (born 1988), Italian swimmer
Federica Ridolfi (born 1974), Italian dancer and a hostess on television
Federica Sallusto (born 1961), Italian biologist
Victoria Federica de Marichalar y de Borbón (born 2000), daughter of the Duchess and Duke of Lugo, and sixth in the line of succession to the Spanish throne