Species Human Entrez 2222 | Human Mouse Ensembl ENSG00000079459 | |
Aliases FDFT1, DGPT, ERG9, SQS, SS, farnesyl-diphosphate farnesyltransferase 1 External IDs MGI: 102706 HomoloGene: 3281 GeneCards: FDFT1 | ||
Farnesyl-diphosphate farnesyltransferase 1 is a protein that in humans is encoded by the FDFT1 gene.
Function
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
References
Farnesyl-diphosphate farnesyltransferase 1 Wikipedia(Text) CC BY-SA