Aliases FZD1 Human Mouse Ensembl ENSG00000157240 | Species Human Entrez 8321 | |
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External IDs MGI: 1196625 HomoloGene: 20750 GeneCards: FZD1 | ||
Frizzled-1 is a protein that in humans is encoded by the FZD1 gene.
Function
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
References
FZD1 Wikipedia(Text) CC BY-SA