Species Human Entrez 11211 | Human Mouse Ensembl ENSG00000111432 | |
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Aliases FZD10, CD350, FZ-10, Fz10, FzE7, hFz10, frizzled class receptor 10 External IDs MGI: 2136761 HomoloGene: 21411 GeneCards: FZD10 | ||
Frizzled-10 is a protein that in humans is encoded by the FZD10 gene. FZD10 has also been designated as CD350 (cluster of differentiation 350).
Function
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
References
FZD10 Wikipedia(Text) CC BY-SA