Aliases FGF10 Human Mouse Ensembl ENSG00000070193 | Species Human Entrez 2255 | |
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External IDs MGI: 1099809 HomoloGene: 3284 GeneCards: FGF10 | ||
Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene.
Function
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of limb bud formation. This gene is also implicated to be a primary factor in the process of wound healing.