FC Shakhtar Donetsk in European football

This is a list of matches of FC Shakhtar Donetsk in Europe. Shakhtar Donetsk participates in European competitions since 1976 after playing its first against Berliner FC Dynamo in the UEFA Cup 1976–77. Since 1997, however, the club continuously participates on annual basis with variable successes, while also taking part in UEFA Champions League competition since 2000. Shakhtar's first qualification to a group stage in a European competition took place in the 2000–01 UEFA Champions League when Shakhtar Donetsk played against Arsenal, Lazio, and Sparta Prague in Group B. While being a constant presence in Champions League group stages, Shakhtar have only reached UEFA Cup/UEFA Europa League group stages twice (2005–06 and 2009–10).

In 2009, Shakhtar Donetsk won the UEFA Cup over Werder Bremen in the final held in Istanbul, thus becoming the first team in the independent Ukraine to win a European trophy. In 2010-11, Shakhtar made it to the quarter-finals of UEFA Champions League, being eliminated by FC Barcelona; this was the first time the team qualified for the knockout phase in Champions League. In 2015–16, despite an awful display in Champions League group stages, Shakhtar was able to qualify to UEFA Europa League knock-out phases by finishing third place in the group; Shakhtar reached the semi-finals after knocking out Schalke 04, Anderlecht and Braga, but were eventually knocked out by title defenders Sevilla.