Kalpana Kalpana (Editor)

Ethyl diazoacetate

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Formula
  
C4H6N2O2

Density
  
1.08 g/cm³

Molar mass
  
114.1 g/mol

Appearance
  
yellow oil

Ethyl diazoacetate httpsuploadwikimediaorgwikipediacommons44

Ethyl diazoacetate (N=N=CHC(O)OC2H5) is a diazo compound and a reagent in organic chemistry. It was discovered by Theodor Curtius in 1883. The compound can be prepared by reaction of the ethyl ester of glycine with sodium nitrite and sodium acetate in water.

It is used in the cyclopropanation of alkenes.

Although the compound is hazardous it is used in chemical industry. Procedures for safe industrial handling have been published

Applications

Tranylcypromine, Trovafloxacin

References

Ethyl diazoacetate Wikipedia