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Epsilonpapillomavirus is a genus of viruses, in the family Papillomaviridae. Bovine serve as natural hosts. There is currently only one species in this genus: the type species Epsilonpapillomavirus 1. Diseases associated with this genus include: fibropapillomas and true epithelial papillomas of the skin.
Contents
Taxonomy
Group: dsDNA
Structure
Viruses in Epsilonpapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length. The genome codes for 6 proteins.
Life Cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Bovine serve as the natural host. Transmission routes are contact.