ATCvet code QA07AA94 (WHO) PubChem CID 56842192 Formula C107H138Cl2N26O31 | CAS Number 11115-82-5 UNII 4GP7CLG9EG Molar mass 2,355.3 g/mol | |
 | ||
Elaine wang regional manager of enramycin at ipema hybiz tv
Enramycin or Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicidus. Enramycin is widely used as a feed additive for pigs and chickens to prevent necrotic enteritis induced by Gram-positive gut pathogens.
Contents
- Elaine wang regional manager of enramycin at ipema hybiz tv
- How to pronounce enramycin
- Mechanism of action
- Spectrum of susceptibility
- Composition
- References
How to pronounce enramycin
Mechanism of action
Enramycin acts as an inhibitor of the enzyme, MurG, which is essential for cell wall biosynthesis in Gram-positive bacteria. MurG catalyzes the transglycosylation reaction in the last step of peptidoglycan biosynthesis. Inhibiting this step greatly compromises cell wall integrity leading to cell lysis.
Spectrum of susceptibility
Enramycin has been found to be very effective against Gram-positive gut pathogens, most notably, Clostridium perfringens; a leading cause of necrotic enteritis. The following represents MIC data for a couple of veterinary pathogens.
Composition
Standard grade enramycin is composed of two main components called enramycin A and enramycin B. These two components are routinely used as analytical reference standards; however, their activity as individual compounds does not appear to be widely studied or characterized.