ATC code A02BB02 (WHO) PubChem CID 5311225 UNII J4IP5Z9DAU CAS ID 73121-56-9 | CAS Number 73121-56-9 ChemSpider 4470744 Molar mass 400.46 g/mol | |
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AHFS/Drugs.com International Drug Names |
Medical vocabulary what does enprostil mean
Enprostil is a synthetic prostaglandin designed to resemble dinoprostone. Enprostil was found to be a highly potent inhibitor of gastric HCl secretion. It is an analog of prostaglandin E2 but unlike this prostaglandin, which binds to and activates all four cellular receptors viz., EP1, EP2, EP3, and EP4 receptors, enprostil is a more selective receptor agonist in that it binds to and activates primarily the EP3 receptor. Consequently, enprostil is expected to have a narrower range of actions that may avoid some of the unwanted side-effects and toxicities of prostaglandin E2. A prospective multicenter randomized controlled trial conducted in Japan found combining enprostil with cimetidine was more effective than cimetidine alone in treating gastric ulcer.