Harman Patil

Enprostil

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ATC code  A02BB02 (WHO)
PubChem CID  5311225
UNII  J4IP5Z9DAU
CAS ID  73121-56-9
CAS Number  73121-56-9
ChemSpider  4470744
Molar mass  400.46 g/mol
Enprostil httpsuploadwikimediaorgwikipediacommonsthu
AHFS/Drugs.com  International Drug Names

Medical vocabulary what does enprostil mean


Enprostil is a synthetic prostaglandin designed to resemble dinoprostone. Enprostil was found to be a highly potent inhibitor of gastric HCl secretion. It is an analog of prostaglandin E2 but unlike this prostaglandin, which binds to and activates all four cellular receptors viz., EP1, EP2, EP3, and EP4 receptors, enprostil is a more selective receptor agonist in that it binds to and activates primarily the EP3 receptor. Consequently, enprostil is expected to have a narrower range of actions that may avoid some of the unwanted side-effects and toxicities of prostaglandin E2. A prospective multicenter randomized controlled trial conducted in Japan found combining enprostil with cimetidine was more effective than cimetidine alone in treating gastric ulcer.

Contents

How to pronounce enprostil


References

Enprostil Wikipedia


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