The film begins with Vizag/Chennai(In tamil version) being shown in 1980 in which a ladies college bus makes its scheduled bus stop. Krishna (Ram), standing at the bus stop, keeps looking at Srinidhi (Tamannaah), whom he loves, but doesn't express it. He has been doing that for the last three years but without any response from her. Srinidhi also likes Krishna, but does not reveal it, as she fears by doing so, she may put her family in trouble. On the last day of the college, Krishna decides to propose to her. So he disguises himself in a 'burqa' and boards the bus. However, the bus conductor recognises him and forces the bus driver to stop the bus. However, before he could stop it, the bus gets involved in an accident. Krishna saves Srinidhi from the mishap, but is killed in the process. Shocked about Krishna's death, Srinidhi dies at the grave of Krishna.
The film moves to 2012 in Paris, where Sravanthi (Tamannah), daughter of the Indian Ambassador to France (Suman) and a medical student, is leading a stifling life due to her father's security around her. She wants to break away from this life and live with freedom. She fantasizes an unidentified person in her dream every day, falls for him and she promises her friends to marry him if her dream comes true, whoever he may be. One day, when her father had to leave the country due to his professional commitments, she stealthily escapes from her home and goes on a tour of the whole country side with her friends and is able to free herself at last from the security around her.
Ram (Ram) is a happy-go-lucky guy who is a headache to his father (Sayaji Shinde) as he does not take life seriously. So his father tricks him and sends him to Paris for a job, which he arranges through his friend (Nagineedu) without the knowledge of Ram. One day Ram sees Sravanthi standing on a railing of the bridge over a river and forces her to get down. They soon get acquainted and friendship blossoms between them. Meanwhile, Sravanthi's father is worried that she has not returned since he left and asks his Chief Security Officer DK (Richard Rishi) to find her. Sravanthi and Ram both want to leave for India. Ram gets his passport by bluffing Sravanthi's father. However, at the airport, he is not able to trace Sravanthi and leaves for India alone. After reaching India, he finds Sravanthi to his surprise at the airport.She tells him to meet a specific doctor in a specific hospital and disappears from his sight. On meeting the doctor, he finds Sravanthi in the hospital ICU. Sravanthi reveals that Ram has been talking to the soul of Sravanthi. She went into a coma after an accident which was a part of conspiracy hatched by DK and his agent in India (Kona Venkat). She is visible only to Ram but not to others, owing to their previous lives.
Ram protects Sravanthi's body when he notices that any harm to her body will harm the soul, by taking her to his aunt (Anu Hassan)'s hospital. His aunt tells him that she can survive and come out of coma if and only if a German medicine is given three doses at exactly the same time (every 48 hours) but at different periods. She goes to a very powerful person who can sense beneath the lives and asks him why Sravanthi is visible only to Ram. The person tells her it is the will of god and after she goes from there he replies to his student that this is happening because Ram and Sravanthi's love failed since the past 6 lives and it wants to fulfil itself in this last life.
First dose is given to Sravanthi's body without much of a problem. Meanwhile, DK tries to kill Sravanthi by having her body kidnapped, but Ram is able to rescue her body and give the second dose. In the end, DK gets hold of Ram when he goes to get the last dose of medicine. After a fight, Sravanthi is given the third and last dose but DK removes the oxygen cylinder and its supply to Sravanthi. He somehow saves her and she recovers, but fails to recognise Ram. Sravanthi's father arrives at the very moment and gets Ram arrested for cheating him. But he later apologies to Ram after learning of the risk he faced to save his daughter, and gets ready to leave Paris that night with Sravanthi. Their car tyre gets punctured and meanwhile, Sravanthi sees the same location she witnesses in her dream and also sees a person kicking a coke tin which hits her. When she goes towards him to see him, the person is none other than Ram. Sravanthi is surprised to this and when she touches Ram's hand she recollects everything that happened between them this life even in her soul form and expresses her love by hugging him. At last they both get married.Ram as Ram/ Krishna
Tamannaah as Sravanthi (Sharmila in the Hindi version)/ Srinidhi
Suman as Sravanthi's father
Richard Rishi as DK, the security commander of Sravanthi's father and the main antagonist.
Y. Kasi Viswanath as a chef at Sravanthi's house
Sayaji Shinde as Ram's father
Anu Hasan as Ram's Aunt
Kona Venkat as Koka Bhai, the Indian agent of DK.
Satya Krishnan as Dr Savitha
Brahmanandam as Pandu Ranga Rao
Suman Setty as Kumar
The film was to be originally produced by Paruchuri Prasad, who produced the film Simha. However, he backed out in the last minute due to budget constraints. Sravanthi Ravi Kishore and Ram decided to do the film "at any cost as this script has the potential to be made as a bilingual". The shooting of the movie started at the end of July 2011 and it took the crew of the film 118 days to complete. The film was shot in Geneva, Switzerland and France over a period of 60 days. The film was shot simultaneously in Tamil and was named Yen Endral Kadhal Enben, with each shot remade twice. Incidentally, this was Ram's debut film in Tamil. Ram had to learn gymnastics to shoot for a song which delayed the shoot for two months. Kona Venkat, who is the dialogue writer for the film, made his debut in this film as one of the antagonists. "After narrating the dialogues of my character", says Venkat, Karunakaran was convinced that "he could only see me and insisted that I do it". Rishi was selected to play the character of DK, a security commander and the main antagonist, in the film. "This is a new dimension, as a villain I missed dancing with the heroines but I believe that a villain should have a strong aim" says Rishi, who previously played the lead roles in films like A Film By Aravind, Bhagyalakshmi Bumper Draw.
Ultimately, the film's failure at the box office meant that the Tamil version of the film did not have a theatrical release.The movie ends with the message that love do not die.
The film received a clean "U" Certificate from the Censor Board of Film Certification. It was scheduled to release on 11 May 2012. But release was postponed as it coincided with the release date of Pavan Kalyan-starrer Gabbar Singh. The film was finally released worldwide on 8 June 2012.
The film mostly received mixed reviews. Idlebrain.com didn't give any rating for the film but criticised that the "screenplay is not gripping, romance feel is ineffective and run-time is excessive for this kind of subject". Rediff.com has given a rating of 1.5 out of a scale of 5 for the film and declared that "Endukante Premanta disappoints". It criticised the script for its "loopholes" but praised the lead pair of Ram and Tamannah as the "heart and soul of the film". Oneindia.com said that it's "Ram's show" and that "if only the youngsters enjoy the slow pace then it is sure to be another hit for Ram and Karunakaran". Bharatstudent.com had given a rating of 2.75/5 for the film and suggested that it "could have been better". Greatandhra.com had given 2.5/5 for the film and described it as "a soul shuttling between death, coma and life". Cinegoer criticised the director of the film and said that the film "is downright ridiculous, we'd rather see his montage shots on Youtube than sit through this montage film". The Times of India rated the film at 2.5/5 and said that the film is "overall, a very underwhelming experience that only comes off in bits and pieces". The Hindu criticised the film to be "like a montage of different films" and director for "throwing logic to the wind", but praised the lead pair of the film for having "done their best to bring some semblance of reality to this fantasy". CNN-IBN too felt that the film "is far from being perfect" and that "the climax is not one bit convincing". However it praised the cast for its performance and the director for his "bold experiment".
The audio of the film was released on 29 April 2012 and launch of the audio was held at annapurna studios on same day. G. V. Prakash Kumar composed the soundtrack, which received positive response. Musicperk.com rated it 7.5/10 quoting "A refreshing musical album which is cool, lovely, soft, breezy, lively and yet trendy".