Elspeth Mc Lachlan (born 22 July 1942) is a world authority on neural pathways within the autonomic nervous system. Her work has included detailed analyses of transmission in autonomic ganglia to studies of the organisation of autonomic nervous pathways and their disorder in pathological states, particularly injuries to peripheral nerves and the spinal cord.
McLachlan was born in Bowral, New South Wales, Australia.
McLachlan was educated at the University of Sydney, from which institution she received Bachelor of Science degree in 1962, and a PhD in 1973, and a Doctor of Science degree in 1994.
1985–1993 – Visiting Professor, Christian-Albrechts-Universität zu Kiel, Germany 1987–1988 – National Health and Medical Research Council Principal Research Fellow and Associate Professor, School of Physiology and Pharmacology, University of New South Wales, Australia1988–1993 – Professor and Head, Department of Physiology & Pharmacology, University of Queensland, Australia1993–2011 – Senior Principal Research Fellow, Prince of Wales Medical Research Institute, Randwick, Australia1997 – Fellow of the Australian Academy of Science (Science 2008) 1999–2001 – Executive Head, Centre for Research Management, National Health & Medical Research Council, Canberra, Australia2000–2003 – Investigador Asociado, Instituto de Neurociencias, Universidad Miguel Hernández, Alicante, Spain2001–2006 – Pro-Vice Chancellor (Research) and Research Professor, University of New South Wales, Australia2007–present – Emeritus Professor, University of New South Wales, Australia2008–2014 – Honorary Research Fellow, School of LIfe Science, University of Glasgow, Glasgow, United Kingdom2011 onwards – Honorary Senior Principal Research Scientist, Neuroscience Research Australia, Randwick, Australia.2009: Honorary Member, Australian Neuroscience Society2008: Honorary Member, Australian Physiological Society2006: Distinguished Achievement Award, Australian Neuroscience Society2003: Centenary Medal for contribution to the Australian community and science in medical research1998: Ramaciotti Medal for Excellence in Biomedical Research1997: Elected Fellow, Australian Academy of Science 1996, 1999: Invitation Fellowship, Japan Society for the Promotion of Science (JSPS)1995 Orbeli Medal, Armenian Academy of Neuroscience1993: Max-Planck-Research Prize (Max-Planck-Forschungspreis) for international collaborative research (with W. Jänig)McLachlan, E.M., Jänig, W., Devor, M. and Michaelis, M. (1993) Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature, Lond. 363, 543-546 Jänig, W. and McLachlan, E.M. (1992) Characteristics of function-specific pathways in the sympathetic nervous system. Trends in Neurosciences 15, 475-481.Sah, P. and McLachlan, E.M. (1991) Calcium-activated K+ currents underlying the afterhyperpolarization in guinea pig vagal neurons: a role for calcium activated calcium release. Neuron 7, 257-264 McLachlan, E.M. and Martin, A.R. (1981). Non-linear summation of end-plate potentials in the frog and mouse. J. Physiol. 311, 307-324 Schmid, A.B., Coppieters, M.W., Ruitenberg, M.J. and McLachlan, E.M. (2013) Local and remote immune-mediated inflammation after mild peripheral nerve compression in rats. Journal of Neuropathology and Experimental Neurology 72, 662-680 Tripovic, D., McLachlan, E.M. and Brock, J.A. (2013) Removal of half the sympathetic innervation does not reduce vasoconstrictor responses in rat tail artery. The Journal of Physiology 591, 2867-2884. McLachlan, E.M. and Hu, P. (2014) Inflammation in Dorsal Root Ganglia After Peripheral Nerve Injury: Effects Of The Sympathetic Innervation. Autonomic Neuroscience: Basic & Clinical 182, 108-117 Tripovic, D., Pianova,S., McLachlan, E.M. and Brock, J.A. (2011) Slow and incomplete sympathetic reinnervation of rat tail artery restores the amplitude of nerve-evoked contractions provided a perivascular plexus is present. AJP Heart and Circulatory Physiology 300, H541-554