Species Human Entrez 8637 | Human Mouse Ensembl ENSG00000243056 | |
Aliases EIF4EBP3, 4E-BP3, 4EBP3, eukaryotic translation initiation factor 4E binding protein 3 External IDs MGI: 1270847 HomoloGene: 37841 GeneCards: EIF4EBP3 | ||
Eukaryotic translation initiation factor 4E-binding protein 3 is a protein that in humans is encoded by the EIF4EBP3 gene.
Contents
Function
This gene encodes a member of the EIF4EBP family which derives it name from proteins that bind to eukaryotic initiation factor 4E and that prevent its assembly into EIF4F. Co-transcription of this gene and the neighboring upstream gene (MASK) generates a transcript (MASK-BP3) which encodes a fusion protein composed of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.
Interactions
EIF4EBP3 has been shown to interact with EIF4E.
References
EIF4EBP3 Wikipedia(Text) CC BY-SA