Entrez 8664 | Ensembl ENSG00000100353 | |
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Aliases EIF3D, EIF3S7, eIF3-p66, eIF3-zeta, eukaryotic translation initiation factor 3 subunit D External IDs MGI: 1933181 HomoloGene: 2782 GeneCards: EIF3D | ||
Eukaryotic translation initiation factor 3 subunit D is a protein that in humans is encoded by the EIF3D gene.
Contents
Function
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex.
Interactions
References
EIF3D Wikipedia(Text) CC BY-SA