Species Human Entrez 83939 | Human Mouse Ensembl ENSG00000144895 | |
 | ||
Aliases EIF2A, EIF-2A, MST089, MSTP004, MSTP089, CDA02, eukaryotic translation initiation factor 2A External IDs MGI: 1098684 HomoloGene: 5969 GeneCards: EIF2A | ||
Eukaryotic translation initiation factor 2A is a protein that in humans is encoded by the EIF2A gene.
Function
EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002).[supplied by OMIM] It has been shown to be important for translation initiation mediated by the HCV IRES under stress conditions by binding to the IRES domain IIId and Met-tRNAiMet.
References
EIF2A Wikipedia(Text) CC BY-SA