Entrez 1917 | Ensembl ENSG00000101210 | |
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Aliases EEF1A2, EEF1AL, EF-1-alpha-2, EF1A, HS1, STN, STNL, EIEE33, MRD38, eukaryotic translation elongation factor 1 alpha 2 External IDs MGI: 1096317 HomoloGene: 121568 GeneCards: EEF1A2 | ||
Gene music using protein sequence of eef1a2 eukaryotic translation elongation factor 1 alpha 2
Elongation factor 1-alpha 2 is a protein that in humans is encoded by the EEF1A2 gene.
Contents
- Gene music using protein sequence of eef1a2 eukaryotic translation elongation factor 1 alpha 2
- Function
- Clinical significance
- Regulation
- References
Function
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas.
Clinical significance
This gene may be critical in the development of ovarian cancer.
Regulation
EEF1A2 is a direct target of miRNA-663 and miRNA-744.
References
EEF1A2 Wikipedia(Text) CC BY-SA