Entrez 8721 | Ensembl ENSG00000107223 | |
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Aliases EDF1, EDF-1, MBF1, CFAP280, endothelial differentiation related factor 1 External IDs MGI: 1891227 HomoloGene: 2809 GeneCards: EDF1 | ||
Endothelial differentiation-related factor 1 is a protein that in humans is encoded by the EDF1 gene.
Contents
Function
This gene encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.
Interactions
EDF1 has been shown to interact with:
References
EDF1 Wikipedia(Text) CC BY-SA