Samiksha Jaiswal (Editor)

Dorothy Warburton

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Nationality
  
Canadian

Academic advisors
  
Clarke Fraser

Spouse
  
Frederick Warburton

Notable award
  
William Allan Award

Institutions
  
Columbia University

Notable awards
  
William Allan Award

Alma mater
  
McGill University

Institution
  
Columbia University


Born
  
12 January 1936 Galt, Ontario, Canada (
1936-01-12
)

Known for
  
Research contributions to the epidemiology of spontaneous abortion

Died
  
26 April 2016, Englewood, New Jersey, United States

Fields
  
Human genetics, Cytogenetics

Dorothy Pamela (DeMontmerency) Warburton (12 January 1936 – 26 April 2016) was a Canadian geneticist whose research focussed on fetal chromosomal abnormalities and reasons for miscarriage. She died at the age of 80 on 26 April 2016 at her home in Englewood, New Jersey.

Contents

Early Life and Education

Dorothy Pamela DeMontmerency was born in the town of Galt, Ontario on January 12, 1936. Her father worked as an industrial chemist while her mother stayed at home to take care of her and her siblings. She took a liking to biology and natural history from an early age and was especially interested in cytogenetics. This interest carried her through her education and she graduated from McGill University in 1957 with a degree in genetics. She continued her work in genetics at McGill under well-known medical geneticist Clarke Fraser. She completed her doctoral degree in 1961 where her work focused on the recurrence risk of spontaneous abortions.

Career

In 1964, Dorothy moved to New York City and took a position as a faculty member at Barnard College of Columbia University. Here, she started training as a human cytogeneticist in the Department of Obstetrics and Gynecology at the Columbia University College of Physicians and Surgeons. Through her time working in the department she quickly recognized the need for a clinical genetic testing lab in the area. In 1969, she founded the Cytogenetics Laboratory at the NewYork-Presbyterian Hospital and Babie's Hospital that was affiliated with the College of Physicians and Surgeons. She was director of the lab for 37 years and remained an associate director until her death. Dorothy’s research over the years of her career centered on four overlapping themes:

  • Clinical and research cytogenetics.
  • The epidemiology of cytogenetic abnormalities.
  • The epidemiology of human spontaneous abortion.
  • The pathology of spontaneous abortion.
  • Personal life

    Dorothy married fellow McGill graduate student Frederick Toney Warburton in 1957. Together they had four children. Dorothy was a big advocate of women balancing both demanding careers and family at the same time. She was frequently met with criticism throughout her career and was denied faculty appointments and tenure because she was a women in science.

    Dorothy shared a rare immune disorder with three of her four children. This condition was known as a neutrophil chemotactic defect and her and her children often suffered from eczema, asthma, and severe allergies. Due to complications from the condition, one of her daughters unexpectedly died at the age of 24.

    Achievements and Awards

    Throughout her career, Dorothy was honoured with many awards and held many achievements and accomplishments. She received the William Allan Award in 2006 for her contributions to medicine and human genetics. Her lab was also one of the first lab's to use in situ hybridization for human gene mapping and were able to identify the sites of ribosomal RNA genes. For this she received the 2014 Distinguished Cytogeneticist Award from the American Cytogenetics Conference.

    References

    Dorothy Warburton Wikipedia