Dolichyl phosphatase

In enzymology, a dolichyl-phosphatase (EC 3.1.3.51) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are dolichyl phosphate and H₂O, whereas its two products are dolichol and phosphate.

This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. The systematic name of this enzyme class is dolichyl-phosphate phosphohydrolase. Other names in common use include dolichol phosphate phosphatase, dolichol phosphatase, dolichol monophosphatase, dolichyl monophosphate phosphatase, dolichyl phosphate phosphatase, polyisoprenyl phosphate phosphatase, polyprenylphosphate phosphatase, and Dol-P phosphatase. This enzyme participates in n-glycan biosynthesis.