Puneet Varma (Editor)

Distigmine

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Routes of administration
  
oral, i.m.

Biological half-life
  
65 h

CAS Number
  
15876-67-2

Molar mass
  
576.322 g/mol

ATC code
  
N07AA03 (WHO)

Excretion
  
renal

PubChem CID
  
27522

Bioavailability
  
4.6%

Distigmine (as distigmine bromide) is a parasympathomimetic. Distigmine is similar to pyridostigmine and neostigmine but has a longer duration of action. It is available as tablets on prescription only. Distigmine has a greater risk of causing cholinergic crisis because of accumulation of the drug being more likely than with neostigmine or pyridostigmine and so distigmine is rarely used as a treatment for myasthenia gravis, unlike pyridostigmine and neostigmine.

References

Distigmine Wikipedia