Routes ofadministration IM, SC Molar mass 281.316 g/mol | Legal status Veterinary use only | |
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Trade names Azidin, Berenil, Ganasag, Pirocide ATCvet code QP51AF01 (WHO) QP51AX07 (WHO) Synonyms 4,4'-(1-Triazene-1,3-diyl)bis(benzenecarboximidamide) CAS Number 536-71-0aceturate: 908-54-3 | ||
Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names (see drugbox). It is effective against certain protozoa such as Babesia, Trypanosoma and Cytauxzoon. The drug may also be effective against certain bacteria including Brucella and Streptococcus.
Chemically it is a di-amidine, and it is used in form of the aceturate (N-acetylglycinate).
The mechanism is not well understood; it probably inhibits DNA replication, but also has affinity to RNA.
Side effects
Acute side effects include vomiting, diarrhoea and hypotension (low blood pressure). Diminazen can harm the liver, kidneys and brain, which is potentially life-threatening; especially camels are susceptible to these effects.
References
Diminazene Wikipedia(Text) CC BY-SA