Kalpana Kalpana (Editor)

Demoxepam

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Biological half-life
  
35–40 hours

PubChem CID
  
13756

UNII
  
8X1XP5M0SB

CAS Number
  
963-39-3

ChemSpider
  
10441314

KEGG
  
D02600

Demoxepam

Demoxepam is a drug which is a benzodiazepine derivative. It is a metabolite of chlordiazepoxide and has anticonvulsant properties and presumably other characteristic benzodiazepine properties.

Synthesis

Demoxepam is also an intermediate in the synthesis of oxazepam; it is also used in one of the syntheses of medazepam. It can be considered directly analogous/synonoymous with the synthesis of chlordiazepoxide, with the exception that instead of methylamine, hydroxide ion is the choice of base; here acid is not used for the cyclodehydration step though.

References

Demoxepam Wikipedia