Dejean is a surname. Notable people with the surname include:
Louis Dejean (1872–1954), French sculptor and engraverMike DeJean (born 1970), American baseball playerJean François Aimé Dejean (1749–1824), French army officer and minister of state in the service of the First French Republic and the First French EmpireJean-Luc Déjean (1921–2006), French writerPhilippe DeJean (1736–c.1809), judge in Fort Detroit until he was captured during the American RevolutionPierre Charles Dejean (1807–1872), French general and politicianPierre François Marie Auguste Dejean (1780–1845), French entomologistJorge Tomás Dejean (1998), Argentinian capo master, odontologist, Juanchila's roommate.