De Keyser, DeKeyser or Dekeyser is a Dutch surname mostly found in Flanders. It translates to "the emperor". People with this name include:
Alexei de Keyser (1967–2004), British television producer
David de Keyser (born 1927), British actor
Eugénie De Keyser (1918–2012), Belgian art historian
Hendrick de Keyser (1565–1621), Dutch sculptor and architect
Jean-Pierre de Keyser, (born 1965) German footballer
Merten de Keyser (died 1536) French painter and publisher working in Antwerp
Nicaise de Keyser (1813–1873), Belgian painter
Pieter de Keyser (1595–1676), Dutch architect and sculptor, son of Hendrick
Polydore de Keyser (1832–1918), British lawyer
Raoul De Keyser (1930–2012), Belgian painter
Thomas de Keyser (1596–1667), Dutch painter and architect, son of Hendrick
Véronique De Keyser (born 1945), Belgian politician
Willem de Keyser (architect) (1603-after 1674), Dutch architect and painter, son of Hendrick
Willem de Keyser (painter) (1647–1692), Flemish painter
Concatenated:
Danny DeKeyser (born 1990), American ice hockey player
Dawn DeKeyser, American television writer and producer
Giovanni Dekeyser (born 1976), Belgian field hockey player
Jérôme Dekeyser (born 1983), Belgian field hockey player
Pierre Louis Dekeyser (1914-1984), French zoologist
Robert Dekeyser (born 1964), Belgian-German entrepreneur
Rudy Dekeyser (born 1976), Belgian molecular biologist and businessman
Tracey DeKeyser (born 1990), American ice hockey player and coach