Darko Dimitrov was born on 21 January 1973, in Skopje, SFR Yugoslavia (present-day Republic of Macedonia), to prominent Macedonian singer and composer, Slave Dimitrov. His family has a rich musical history — his grandfather was the prominent opera and traditional music singer, Blagoja Petrov Karagjule. Darko Dimitrov graduated at the Academy of Music in Skopje and he works in his family recording studio called "Studio Dimitrovi" along with his father and his brother Oliver, the latter being notable for producing the debut album of the ska-punk band, Superhiks.
One of his first production hits was "Otvori go Pendžerčeto", performed by the rap group Nulta Pozitiv and featuring the popular folk singer, Mitre Mitrevski.
After producing for mostly hip hop and pop rap oriented artists during the early 90s, Darko Dimitrov moved on to work in the pop music industry. From 1996 onwards, he produced several chart-topping hits for artists such as Nokaut, Karolina Gočeva, Toše Proeski, Kaliopi, Elena Risteska, Jovan Jovanov, Tamara Todevska, Tijana Dapčević, Vlado Janevski, Lambe Alabakoski, Vrčak, Vlatko Lozanovski, Esma, Darko Pančev's wife Maja Grozdanovska Pančeva, Besa (singer), Elhaida Dani , Gentiana Ismajli, Anjeza Shahini, Ledina Çelo, Leonora Jakupi, Rosela Gjylbegu, Altuna Sejdiu, Jonida, Vesa, Rovena, Pirro Cako, Juliana Pasha, Kejsi Tola, Greta koci, Elvana Gjata, Aurela Gaçe, Rafet El Roman, Aleksandra Radović, Jelena Tomasevic, Ivo Gamulin, Jovana Nikolic, Sergej Ćetković, Hari (Hajrudin) Varešanović, Emina Jahović, Arilena Ara, and 2007 Eurovision Song Contest winner Marija Šerifović among many other domestic and foreign pop stars.
In 1999, Dimitrov released compilation album featuring music from various artists which he has produced. The album, 100% Hits: The Best of Darko Dimitrov broke national sales records.
His songs have participated in many notable pop music festivals such as Skopje Fest, MakFest, Ohrid Fest, Sunčane Skale and the Budva Music Festival in Montenegro, the FERAS Radio Festival in Serbia, Croatian Radio Festival, the Split Festival in Croatia, Dora Croatia, the Pamukkale Festival in Turkey, the Golden Stag in Romania, Kënga Magjike in Albania and the 2006 European Song Festival for Children with Special Needs, Junior Eurovision Song 2011.
Dimitrov produced and composed "Ninanajna", the Macedonian entry in the 2006 Eurovision Song Contest. The song was performed in both the Macedonian and English languages by Elena Risteska and received 56 points, placing 12th, which is the biggest success for the country thus far.he make the song " Ne volis je znam " on Marija Serifovic opening show at Eurovision song contest 2008 in Belgrade . In 2013 he participate in eurosong like a co-writer and co-composer of "Pred da se razdeni" ("Before the sunrise"; performed by Esma Redžepova and Vlatko Lozanoski. In 2014 with Tijana To the Sky". In 2015 he Arranged and produced "I'm Alive for Elhaida Dani"
Darko Dimitrov has won over 30 awards in the "best producer", "best composer" and "best arranger" categories. and his songs win on many festivals and got may other awards. He co-founded the M2 Productions record label along with Ivo Jankovski, the former manager of the eminent Macedonian groups Leb i Sol, Arhangel and Anastazija.
M2 Productions organised several talent shows, from which several current Macedonian pop stars emerged. Among these: Elena Risteska, Lambe Alabakoski, Aleksandra Pileva, 4play, Emil Arsov, Tuna, Dimitar Andonovski, Bojana Atansovska....
As an eminent songwriter, Darko Dimitrov is supported by the Ministry of Culture of the Republic of Macedonia.