She currently hosts a radio show with her sister called "Danielle and Jodie", Salford City Radio, every Tuesday at 6:00.
Her sister is glamour model Jodie Nicholls.
In June 2006, she married Dean Holden, of Scottish Premier League side Falkirk. Dean left Rochdale in May 2012. Danielle and Dean live in Worsley and have two children.
The couple's daughter Cici Milly Holden died from Meningococcal disease in May 2012, aged just 17 months old, whilst on a family holiday in Lanzarote.
Nicholls started dancing at the age of 9. At 15 she became the All England Modern Dance Champion, and had also passed two Royal Academy of Dance ballet exams with honours. She was then studying at Moorside High School, Swinton. After finishing a two-year course in Performing Arts at Oldham College, at the age of 18, Nicholls became a member of Pure Gossip, and stayed with the group for a year.
In May 1998, out of 900 applicants, she was chosen to present CITV (then known as CiTV), which ran live, six days a week, and had an audience of four million viewers. Amongst the illustrious stars she interviewed on the show were: Britney Spears, Justin Timberlake and Victoria Beckham. Such was ITV's faith in Danielle, that they sent her to Australia to film a behind-the-scenes special on Home and Away. On 1 May 2000, Danielle took on one of her most challenging jobs and presented the live ITV Day of Promise show with Eamonn Holmes and Carol Vorderman. In 2000 she also presented the live CITV game show Mad for It.
After more than three years as a presenter ever on CITV, Nicholls left in December 2001. She did have a brief return to children's TV as a presenter in the Saturday morning show Diggit. She continued as a presenter of three series of the hit Channel 5 celebrity karaoke show, Night Fever, until 2002. In 2003, Nicholls toured the country with Mark Speight in the Speight of the Art roadshow.
She appeared in the second series of Sooty Heights.
From 2000 to 2002 Danielle co-hosted Night Fever on UK Channel 5, and its spin-off Beach Fever.
In July 2002, Nicholls took over the continuity announcements for Sky Movies. She left in October 2003.
In 2004, Nicholls presented another series, broadcast on Tyne Tees; The Unprofessionals where, along with a co-presenter, she was given different tasks to perform including pole dancing, a children's party entertainer, a drain unblocker and a taxidermist.
During Christmas 2004-05, Nicholls was a presenter on the NTL Broadband UK channel.
In 2006, Nicholls became one of the presenters of Text2Date, a programme which encourages participants to meet and date by using mobile phone text messages. The show is broadcast nightly from 2300 - 0200 on the Performance Channel on Sky Digital channel 271.
Nicholls' enthusiasm and personality has led to numerous guest appearances on programmes, including Trisha, The Last Word, This Morning, Bedrock, Boys & Girls, Dick & Dom in da Bungalow, Sport on 5 and Granada Soccer Night. She was also the voice behind the late night documentary series about North West nightlife called Party Fever which was shown on Granada.
Danielle currently co-presents a radio show, called "Danielle and Jodie", with her sister on 94.4FM, Salford City Radio, every Tuesday at 18:00.
Nicholls took a brief absence from CITV in December 2000, when she took to the stage displaying her acting, singing and dancing talents, playing the leading role of Snow White at the Opera House in Manchester. The following years, she appeared as Snow White in the other successful pantomimes at Northampton, Sunderland, Southport and Weston-super-Mare, and in December 2005/January 2006, playing another leading role as Fairy Crystal in the Snow White pantomime at the Grand Opera House in York.
As well as the annual pantomime performances, in 2004 she also starred on stage in the Hammond Production Group's The Young Ones Summer Holiday in Worthing.
Danielle is currently recording her first album under a pseudonym.