Aliases DTNB Human Mouse Ensembl ENSG00000138101 | Species Human Entrez 1838 | |
External IDs MGI: 1203728 HomoloGene: 74875 GeneCards: DTNB | ||
Beta dystrobrevin also known as DTNB is a protein which in humans is encoded by the DTNB gene.
Function
This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
References
DTNB Wikipedia(Text) CC BY-SA